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SENP3 antibody - N-terminal region (ARP55322_P050)

100 ul

Regular Price: $289.00

Special Price: $215.00

In Stock

Conjugation Options

ARP55322_P050-FITC Conjugated

ARP55322_P050-HRP Conjugated

ARP55322_P050-Biotin Conjugated

Gene Symbol:
SENP3
NCBI Gene Id:
26168
Official Gene Full Name:
SUMO1/sentrin/SMT3 specific peptidase 3
Protein Name:
Sentrin-specific protease 3
Swissprot Id:
Q9H4L4
Protein Accession #:
NP_056485
Nucleotide Accession #:
NM_015670
Alias Symbols:
DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3
Replacement Item:
This antibody may replace item sc-111446 from Santa Cruz Biotechnology.
Description of Target:
SENP3 is a protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. SENP3 deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability.
Protein Size (# AA):
574
Molecular Weight:
65kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IF, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SENP3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SENP3.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human SENP3
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-SENP3 (ARP55322_P050)
Peptide Sequence:
Synthetic peptide located within the following region: PPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEE
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
HIF1A; EP300; UBC; SUMO2; WDR5; ASH2L; KMT2D; RBBP5; KMT2A; MEN1; RNF2; HECW2; SOX2; LAS1L; PELP1; CDK6; CDK4; MOV10; CHCHD4; DHX15; ILF3; TRIM63; TRIM54; USP21; USP15; CDKN2A; RPS18; RPS11; RPS8; RPS4X; RPLP0; NPM1; PIDD1; NR1H2; TP53; MDM2; STUB1; HSP90
Blocking Peptide:
For anti-SENP3 (ARP55322_P050) antibody is Catalog # AAP55322 (Previous Catalog # AAPP33153)
Datasheets/Manuals:
Printable datasheet for anti-SENP3 (ARP55322_P050) antibody
Sample Type Confirmation:

SENP3 is strongly supported by BioGPS gene expression data to be expressed in 721_B. HeLa

Target Reference:
Haindl,M., (2008) EMBO Rep. 9 (3), 273-279

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