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Eotaxin 2 Antibody (OAPA00028)

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Gene Symbol:
Eotaxin 2
NCBI Gene Id:
Protein Name:
C-C motif chemokine 24
Swissprot Id:
Protein Accession #:
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express Eotaxin 2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express Eotaxin 2.
Reconstitution and Storage:
Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4oC.
Datasheets / Downloads:
Application Info:
Direct ELISA, Western Blot, Immuneprecipitation, TiterBy direct ELISA, 1:10,000 dilution will yield 0.4 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).
Product Introduction: Eotaxin-2, also called MPIF2 & Ck 6, is a novel CC chemokine produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Furthermore, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which includes C-terminal truncation, contains 78 amino acids (92 amino acids for the mouse homolog, without C-terminal truncation). CCL24 functions as a chemotactic chemokine for resting t-lymphocytes, and eosinophils. CCL24 has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. CCL24 is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line and binds to CCR3.
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