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Now Offering Over 102,157 Antibodies & 44,722 Antigens!

PRKACB Antibody (OAEE00519)

0.1 mg
$190.00
In Stock
Gene Symbol:
PRKACB
NCBI Gene Id:
5567
Official Gene Full Name:
cAMP-dependent protein kinase catalytic subunit beta
Protein Name:
cAMP-dependent protein kinase catalytic subunit beta
Swissprot Id:
P22694
Replacement Item:
This antibody may replace item sc-28315 from Santa Cruz Biotechnology.
Host:
Mouse
Clonality:
Monoclonal
Purification:
Purified by protein A
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PRKACB.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PRKACB.
Immunogen:
Peptide corresponding to amino acids ESPAQNTAHLDQFERIK of human proteinkinase A c alpha (PKAc alpha).
Species Reactivity:
Human
Reconstitution and Storage:
Store at 2-8C. Do not freeze. Do not use after expiration date stamped on vial label.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-PRKACB (OAEE00519) antibody
Specificity:
The antibody 6D2.1 strongly reacts with human proteinkinase A catalytic (PKAc) alpha subunit, and weakly with PKAc gamma subunit (both around 40 kDa). The recognized epitope of PKAc alpha is identical between man, sheep, pig, ox and dog.
Formulation:
Purified
Clone:
6D2.1
Purity:
> 95% (by SDS-PAGE)
Isotype:
IgG1
Storage Buffer:
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Target Reference:
Komagiri Y, Kitamura N.: Comparison of effects of PKA catalytic subunit on I(h) and calcium channel currents in rat dorsal root ganglion cells. Biomed Res. 2007 Aug;28(4):177-89.
Ferraris JD, Persaud P, Williams CK, Chen Y, Burg M.B.: cAMP-independent role of PKA in tonicity-induced transactivation of tonicity-responsive enhancer/ osmotic response element-binding protein. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16800-5.
Doucas V, Shi Y, Miyamoto S, West A, Verma I, Evans R.M.: Cytoplasmic catalytic subunit of protein kinase A mediates cross-repression by NF-kappa B and the glucocorticoid receptor. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):11893-8.
Beebe SJ, Oyen O, Sandberg M, Frøysa A, Hansson V, Jahnsen T.: Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis--representing a third isoform for the catalytic subunit of cAMP-dependentprotein kinase. Mol Endocrinol. 1990 Mar;4(3):465-75.
Kiger JA Jr, Eklund JL, Younger SH, O'Kane C.J.: Transgenic inhibitors identify two roles for protein kinase A in Drosophiladevelopment. Genetics. 1999 May;152(1):281-90.
Protocol:
Tips Information:

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