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PDK4 antibody - N-terminal region (ARP32787_P050)

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100 ul

Regular Price: $289.00

Special Price: $215.00

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Conjugation Options

ARP32787_P050-FITC Conjugated

ARP32787_P050-HRP Conjugated

ARP32787_P050-Biotin Conjugated

Gene Symbol:
PDK4
NCBI Gene Id:
5166
Official Gene Full Name:
Pyruvate dehydrogenase kinase, isozyme 4
Protein Name:
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial
Swissprot Id:
Q16654
Protein Accession #:
NP_002603
Nucleotide Accession #:
NM_002612
Alias Symbols:
FLJ40832
Replacement Item:
This antibody may replace item sc-130841 from Santa Cruz Biotechnology.
Description of Target:
PDK4 is a member of the PDK/BCKDK protein kinase family and is a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism.This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
Protein Size (# AA):
411
Molecular Weight:
46kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PDK4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PDK4.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human PDK4
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 100%; Rat: 92%
Complete computational species homology data:
Anti-PDK4 (ARP32787_P050)
Peptide Sequence:
Synthetic peptide located within the following region: MKAARFVLRSAGSLNGAGLVPREVEHFSRYSPSPLSMKQLLDFGSENACE
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; DLAT; PDK4; PDHA1; TRIM63;
Blocking Peptide:
For anti-PDK4 (ARP32787_P050) antibody is Catalog # AAP32787 (Previous Catalog # AAPP03806)
Datasheets/Manuals:
Printable datasheet for anti-PDK4 (ARP32787_P050) antibody
Target Reference:
Kimura,K., (2006) Genome Res. 16 (1), 55-65
 
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