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NR4A1 antibody - N-terminal region (ARP31941_T100)

100 ul

Regular Price: $229.00

Special Price: $215.00

In Stock

Conjugation Options

ARP31941_T100-FITC Conjugated

ARP31941_T100-HRP Conjugated

ARP31941_T100-Biotin Conjugated

Gene Symbol:
NR4A1
NCBI Gene Id:
3164
Official Gene Full Name:
Nuclear receptor subfamily 4, group A, member 1
Protein Name:
Nuclear receptor subfamily 4 group A member 1
Swissprot Id:
P22736
Protein Accession #:
NP_775180
Nucleotide Accession #:
NM_173157
Alias Symbols:
HMR, N10, TR3, NP10, GFRP1, NAK-1, NGFIB, NUR77
Replacement Item:
This antibody may replace item sc-112240 from Santa Cruz Biotechnology.
Description of Target:
NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.
Protein Size (# AA):
598
Molecular Weight:
66kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NR4A1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NR4A1.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human NR4A1
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%
Complete computational species homology data:
Anti-NR4A1 (ARP31941_T100)
Peptide Sequence:
Synthetic peptide located within the following region: GTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMD
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
KRTAP10-5; KRTAP10-1; LONRF1; PGBD1; BCL2L10; CDKN2D; BCL2A1; BCL2; TUBB4A; VASP; ANKIB1; CUTA; NFKB1; SMAD3; LSS; HADHA; GLUD1; GK; CPT1A; SERPING1; ABCC6; ABCC13; SOCS4; ABCG8; DIABLO; HCVgp1; ABCA5; CHEK2; SUGT1; PRDX4; PRDX6; CHD1L; ABCB11; ARHGEF5; U
Blocking Peptide:
For anti-NR4A1 (ARP31941_T100) antibody is Catalog # AAP31941
Datasheets/Manuals:
Printable datasheet for anti-NR4A1 (ARP31941_T100) antibody
Target Reference:
Lu,L., et al., (2004) J. Clin. Endocrinol. Metab. 89 (8), 4113-4118
Publications:

Bian, XL; Chen, HZ; Yang, PB; Li, YP; Zhang, FN; Zhang, JY; Wang, WJ; Zhao, WX; Zhang, S; Chen, QT; Zheng, Y; Sun, XY; Wang, XM; Chien, KY; Wu, Q; Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation. 8, 14420 (2017). IHC, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 28240261

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