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NR1H3 Antibody (OAAN00749)

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Gene Symbol:
NR1H3
NCBI Gene Id:
10062
Official Gene Full Name:
nuclear receptor subfamily 1 group H member 3
Protein Name:
Oxysterols receptor LXR-alpha
Swissprot Id:
Q13133
Protein Accession #:
NP_001123573.1
Nucleotide Accession #:
NM_001130101.2
Alias Symbols:
LXR-a, LXRA, RLD-1, LXRA, LXR-a, RLD-1, nuclear receptor subfamily 1 group H member 3, Oxysterols receptor LXR-alpha, NR1H3
Description of Target:
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Molecular Weight:
50 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified against immunogen
Application:
WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NR1H3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NR1H3.
Immunogen:
Recombinant protein of human NR1H3
Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Datasheets/Manuals:
Printable datasheet for anti-NR1H3 (OAAN00749)
Preservative:
0.02% Sodium Azide
Conjugation:
Unconjugated
Isotype:
IgG
Application Info:
WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200
Storage Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Protocol:
Tips Information:

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