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NFE2L2 Antibody - middle region (OAGA02126)

100 ul
$289.00
In Stock
Gene Symbol:
NFE2L2
NCBI Gene Id:
4780
Official Gene Full Name:
nuclear factor, erythroid 2-like 2
Swissprot Id:
Q16236
Alias Symbols:
NRF2 antibody, NFE2L2 antibody, nuclear factor erythroid-derived 2-like 2 antibody, nuclear factor, erythroid derived 2, like 2 antibody, NF-E2-related factor 2 antibody, HEBP1 antibody
Replacement Item:
This antibody may replace item sc-127242, HPA002990
Description of Target:
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress and the regulation of cellular redox conditions. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Molecular Weight:
68 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Purified by antigen-affinity chromatography.
Application:
ICC, IF, IHC-FFPE, IP, WB
Tissue Tool:
Find tissues and cell lines supported to express NFE2L2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NFE2L2.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human NRF2. The exact sequence is proprietary.
Species Reactivity:
Human, Mouse, Rat, Alligator, Bird, Plant
Predicted Homology Based on Immunogen Sequence:
Rhesus Monkey (99%), Bovine (84%)
Product Format:
Liquid. 1XPBS, 20% Glycerol (pH 7). 0.025% ProClin 300 was added as a preservative.
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Concentration:
0.11 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-NFE2L2 (OAGA02126) antibody
Isotype:
IgG
Application Info:
ICC/IF: 1:100-1:1000
IHC-FFPE 1:100-1:1000
IP 1:100-1:500
WB 1:500-1:3000
Additional Information:
Positive Controls: C8D30 , 3xFlag-human NFE2L2-transfected 293T , MDA-MB-231 nuclear extract , MDA-MB-231 nuclear extract (30uM tBHQ, 4hr) , HepG2 (10 μM MG132 treatment for 15 hr)
Cellular Localization: Cytoplasm , cytosol , Nucleus
Protocol:
Tips Information:

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