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MSH6 antibody - N-terminal region (ARP41348_P050)

100 ul

Regular Price: $289.00

Special Price: $215.00

In Stock

Conjugation Options

ARP41348_P050-FITC Conjugated

ARP41348_P050-HRP Conjugated

ARP41348_P050-Biotin Conjugated

Gene Symbol:
MSH6
NCBI Gene Id:
2956
Official Gene Full Name:
MutS homolog 6 (E. coli)
Protein Name:
DNA mismatch repair protein Msh6
Swissprot Id:
P52701
Protein Accession #:
NP_000170
Nucleotide Accession #:
NM_000179
Alias Symbols:
GTBP, HNPCC5, HSAP
Replacement Item:
This antibody may replace item sc-10798 from Santa Cruz Biotechnology.
Description of Target:
This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide bind
Protein Size (# AA):
1360
Molecular Weight:
153kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MSH6.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MSH6.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human MSH6
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%
Complete computational species homology data:
Anti-MSH6 (ARP41348_P050)
Peptide Sequence:
Synthetic peptide located within the following region: ISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
BRCA1; UBC; SUMO2; PCNA; POLK; SAMHD1; GANAB; HYOU1; SUPT5H; XRCC6; ATP6V1B2; UBD; HDAC11; MSH2; CSNK2A1; SUPT16H; MSH3; MLH1; PMS2; RAD9A; RAD1; MUTYH; HUS1; SLX4; CUL3; NEDD8; FBXO25; SIRT7; XRCC5; PRKDC; BLM; TP53; RAD51; PMS1; SMARCAD1; CHAF1A; DTL; S
Blocking Peptide:
For anti-MSH6 (ARP41348_P050) antibody is Catalog # AAP41348 (Previous Catalog # AAPS01507)
Datasheets/Manuals:
Printable datasheet for anti-MSH6 (ARP41348_P050) antibody
Target Reference:
Magnusson,S., (er) Fam. Cancer (2008) In press

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