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MCL1 Antibody (OAAB21891)

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100 ul
$320.00
In Stock
Gene Symbol:
MCL1
NCBI Gene Id:
4170
Official Gene Full Name:
myeloid cell leukemia 1
Swissprot Id:
Q07820
Protein Accession #:
NP_001184249.1
Nucleotide Accession #:
NM_001197320.1
Alias Symbols:
TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT
Replacement Item:
This antibody may replace item sc-121559, HPA008455
Description of Target:
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Molecular Weight:
37 kDa
Host:
Rabbit
Clonality:
Polyclonal
Application:
WB, IF, IHC-P
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MCL1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MCL1.
Species Reactivity:
Human, Mouse
Predicted Homology Based on Immunogen Sequence:
Human, Mouse
Product Format:
Liquid
Reconstitution and Storage:
Store at 2-8C for up to 6 months. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets / Downloads:
Printable datasheet for anti-MCL1 (OAAB21891) antibody
Preservative:
0.03% Proclin300 and 50% glycerol
Formulation:
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Additional Information:
Function: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Protocol:
Tips Information:
 
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