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MAPK14 Antibody (Phospho-Tyr182) (OAAN02880)

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Gene Symbol:
MAPK14
NCBI Gene Id:
1432
Official Gene Full Name:
mitogen-activated protein kinase 14
Protein Name:
Mitogen-activated protein kinase 14
Swissprot Id:
Q16539
Protein Accession #:
NP_001306.1
Nucleotide Accession #:
NM_001315.2
Alias Symbols:
RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15,-SerAPK2A, p38ALPHA, RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15,-SerAPK2A, p38ALPHA, mitogen-activated protein kinase 14, Mitogen-activated protein kinase 14, MAPK14
Description of Target:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Molecular Weight:
43 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified against immunogen
Application:
WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MAPK14.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MAPK14.
Immunogen:
A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Tyr182 of human MAPK14
Species Reactivity:
Human, Mouse, Rat
Product Format:
WB 1:500~2000
IHC 1:50~200
IF 1:50~200
Reconstitution and Storage:
Store at -20°C. Avoid repeated freeze/thaw cycles.
Datasheets/Manuals:
Printable datasheet for anti-MAPK14 (OAAN02880)
Target Post-Translational Modification:
Phospho-Tyr182
Conjugation:
Unconjugated
Isotype:
IgG
Application Info:
WB 1:500~2000
IHC 1:50~200
Protocol:
Tips Information:

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