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Now Offering Over 102,157 Antibodies & 44,722 Antigens!

MAPK14 Antibody (OASG05517)

100 uL
$215.00
In Stock
Gene Symbol:
MAPK14
NCBI Gene Id:
1432; 26416;
Official Gene Full Name:
mitogen-activated protein kinase 14
Swissprot Id:
Q16539, P47811, P70618
Alias Symbols:
MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A, Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein
Replacement Item:
This antibody may replace item sc-114258 from Santa Cruz Biotechnology.
Description of Target:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Molecular Weight:
40 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Application:
WB, IHC, IF, ELISA
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MAPK14.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MAPK14.
Immunogen:
Synthesized peptide derived from human p38 around the non-phosphorylation site of T180. Location: 120-200aa.
Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-MAPK14 (OASG05517) antibody
Specificity:
p38 Polyclonal Antibody detects endogenous levels of p38 protein.
Isotype:
IgG
Application Info:
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;
Protocol:
Tips Information:

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