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KRAS Antibody - FITC Conjugated (OACA01930)

100 ug
$299.00
In Stock
Gene Symbol:
KRAS
NCBI Gene Id:
3845
Official Gene Full Name:
GTPase KRas
Protein Name:
GTPase KRas
Swissprot Id:
P01116
Protein Accession #:
NP_004976.2; NP_203524.1; XP_006719132.1
Nucleotide Accession #:
NM_004985.4; NM_033360.3; XM_006719069.2
Replacement Item:
This antibody may replace item sc-30 from Santa Cruz Biotechnology.
Description of Target:
The gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein G purified
Application:
WB, ELISA
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express KRAS.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express KRAS.
Immunogen:
Recombinant human GTPase KRas protein (2-168AA)
Species Reactivity:
Human
Product Format:
Liquid 0.01M PBS (pH 7.4) with 0.03% Proclin300 and 50% glycerol
Reconstitution and Storage:
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Concentration:
Varies by lot. See vial for exact concentration.
Datasheets/Manuals:
Printable datasheet for anti-KRAS (OACA01930) antibody
Conjugation:
FITC-conjugated
Purity:
> 95%
Isotype:
IgG
Target Reference:
[1] Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene.'McGrath J.P., Capon D.J., Smith D.H., Chen E.Y., Seeburg P.H., Goeddel D.V., Levinson A.D.Nature 304:501-506(1983)
[2] Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1.'Shimizu K., Birnbaum D., Ruley M.A., Fasano O., Suard Y., Edlund L., Taparowsky E., Goldfarb M., Wigler M.Nature 304:497-500(1983)
[3] Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations.'Capon D.J., Seeburg P.H., McGrath J.P., Hayflick J.S., Edman U., Levinson A.D., Goeddel D.V.Nature 304:507-513(1983)
Protocol:
Tips Information:

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