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HTR3E antibody - middle region (ARP35532_P050)

100 ul

Regular Price: $289.00

Special Price: $215.00

In Stock

Conjugation Options

ARP35532_P050-FITC Conjugated

ARP35532_P050-HRP Conjugated

ARP35532_P050-Biotin Conjugated

Gene Symbol:
HTR3E
NCBI Gene Id:
285242
Official Gene Full Name:
5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
Protein Name:
5-hydroxytryptamine receptor 3E
Swissprot Id:
A5X5Y0
Protein Accession #:
NP_872395
Nucleotide Accession #:
NM_182589
Alias Symbols:
5-HT3c1, MGC120035, MGC120036, MGC120037, 5-HT3E, 5-HT3-E
Replacement Item:
This antibody may replace item sc-515279 from Santa Cruz Biotechnology.
Description of Target:
HTR3E belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
Protein Size (# AA):
471
Molecular Weight:
53kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IF, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HTR3E.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HTR3E.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human HTR3E
Species Reactivity:
Dog, Horse, Human, Rabbit
Predicted Homology Based on Immunogen Sequence:
Dog: 100%; Horse: 83%; Human: 100%; Rabbit: 83%
Complete computational species homology data:
Anti-HTR3E (ARP35532_P050)
Peptide Sequence:
Synthetic peptide located within the following region: RWLHSLLLHCNSPGRCCPTAPQKENKGPGLTPTHLPGVKEPEVSAGQMPG
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide:
For anti-HTR3E (ARP35532_P050) antibody is Catalog # AAP35532 (Previous Catalog # AAPP06772)
Datasheets/Manuals:
Printable datasheet for anti-HTR3E (ARP35532_P050) antibody
Target Reference:
Peters,J.A., Biochem. Soc. Trans. 32 (PT3), 547-552 (2004)

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