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HDAC1 Antibody (OAGA01311)

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100 ul
$289.00
In Stock
Gene Symbol:
HDAC1
NCBI Gene Id:
3065
Official Gene Full Name:
histone deacetylase 1
Swissprot Id:
Q13547
Alias Symbols:
HD1, RPD3, GON-10, RPD3L1
Replacement Item:
This antibody may replace item sc-125435, HPA029693
Description of Target:
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Purified by antigen-affinity chromatography.
Application:
IF, IHC-P, IP, WB, CHIP
Tissue Tool:
Find tissues and cell lines supported to express HDAC1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HDAC1.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human HDAC1. The exact sequence is proprietary.
Species Reactivity:
Human, Mouse
Product Format:
Liquid. 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Concentration:
1mg/ml
Datasheets / Downloads:
Printable datasheet for anti-HDAC1 (OAGA01311) antibody
Isotype:
IgG
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)], ICC/IF: 1:100-1:1000, IP: 1:100-1:500, ChIP. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
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Protocol:
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