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Goat Anti-CYBB / GP91-PHOX Antibody (OAEB01528)

100 ug
$289.00
In Stock
Gene Symbol:
CYBB
NCBI Gene Id:
1536
Protein Name:
Cytochrome b-245 heavy chain
Swissprot Id:
P04839
Protein Accession #:
NP_000388.2
Alias Symbols:
CYBB, cytochrome b-245, beta polypeptide (chronic granulomatous disease), CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, cytochrome b-245, beta polypeptide
Replacement Item:
This antibody may replace item sc-130543 from Santa Cruz Biotechnology.
Host:
Goat
Clonality:
Polyclonal
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CYBB.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CYBB.
Species Reactivity:
Dog, Human, Mouse, Pig, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Dog: 92%; Human: 100%; Mouse: 83%; Pig: 83%; Rabbit: 83%; Rat: 83%
Complete computational species homology data:
CYBB Antibody (OAEB01528)
Peptide Sequence:
C-SYLNFARKRIKNP
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Datasheets/Manuals:
Printable datasheet for anti-CYBB antibody - OAEB01528
Purity:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:2000.
Western Blot: Approx 85Da band observed in Human Peripheral Blood Mononucleocytes ysates (calculated MW of 65.3kDa according to NP_000388.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Teahan et al, Nature. 1987 Jun 25-Jul 1;327(6124):720-1. PMID: 3600769). Recommended concentration: 0.03-0.1ug/ml.
Additional Information:
Reactivity Info: Tested: Human; Expected: Human, Dog
Target Reference:
* Zhu C, Lindsey S, Konieczna I, Eklund EA.; Constitutive activation of SHP2 protein tyrosine phosphatase inhibits
ICSBP-induced transcription of the gene encoding gp91PHOX during myeloid
differentiation.; J Leukoc Biol. 2008 Mar;83(3):680-91.; Pubmed 18089853

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