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G6PD antibody - middle region (ARP58469_P050)

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100 ul
$289.00
In Stock

Conjugation Options

ARP58469_P050-FITC Conjugated

ARP58469_P050-HRP Conjugated

ARP58469_P050-Biotin Conjugated

Gene Symbol:
G6PD
NCBI Gene Id:
2539
Official Gene Full Name:
Glucose-6-phosphate dehydrogenase
Protein Name:
Glucose-6-phosphate 1-dehydrogenase
Swissprot Id:
P11413
Protein Accession #:
NP_000393
Nucleotide Accession #:
NM_000402
Alias Symbols:
G6PD1
Replacement Item:
This antibody may replace item sc-173874 from Santa Cruz Biotechnology.
Description of Target:
G6PD is a glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Protein Size (# AA):
515
Molecular Weight:
57kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express G6PD.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express G6PD.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human G6PD
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Predicted Homology Based on Immunogen Sequence:
Cow: 85%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 86%; Sheep: 83%
Complete computational species homology data:
Anti-G6PD (ARP58469_P050)
Peptide Sequence:
Synthetic peptide located within the following region: VTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRI
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
G6PD; SUMO2; UBC; MDM2; CKB; CAPN1; ALDH7A1; ZNF622; ZFYVE19; UBFD1; CNDP2; ISOC1; MAT2B; ERP44; YWHAQ; SLC9A3R1; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; EIF4H; VCL; UBE2V1; TGM2; PPP1R2; PGD; PAK2; LDHB; SFN; GNS; GLA; GBP2; EIF5; BAG3; FN1; CCT4; HARS; SUMO4
Blocking Peptide:
For anti-G6PD (ARP58469_P050) antibody is Catalog # AAP58469 (Previous Catalog # AAPP34520)
Datasheets/Manuals:
Printable datasheet for anti-G6PD (ARP58469_P050) antibody
Sample Type Confirmation:

G6PD is supported by BioGPS gene expression data to be expressed in MCF7

Target Reference:
Langbein,S., (2008) Int. J. Cancer 122 (11), 2422-2428
 
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