website statistics

Now Offering Over 102,157 Antibodies & 44,722 Antigens!

FYN Antibody (OAEE00393)

Scroll Horizontally to view all Images
Print Page
  • Let us Help: Ask a Question
0.1 mg
$230.00
In Stock
Gene Symbol:
FYN
NCBI Gene Id:
2534
Official Gene Full Name:
Tyrosine-protein kinase Fyn
Protein Name:
Tyrosine-protein kinase Fyn
Swissprot Id:
P06241
Replacement Item:
This antibody may replace item sc-115186, HPA023887
Host:
Mouse
Clonality:
Monoclonal
Purification:
Purified by protein A
Application:
IP, WB, IHC-P, ICC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express FYN.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express FYN.
Immunogen:
Bacterially expressed recombinant fragment of human Fyn (aa 7-176).
Species Reactivity:
Mouse, Human
Reconstitution and Storage:
Store at 2-8C. Do not freeze. Do not use after expiration date stamped on vial label.
Concentration:
1 mg/ml
Datasheets / Downloads:
Printable datasheet for anti-FYN (OAEE00393) antibody
Specificity:
The antibody FYN-01 reacts with Fyn, a 59 kDa non-receptor Src-family protein tyrosine kinase.
Formulation:
Purified
Clone:
FYN-01
Purity:
> 95% (by SDS-PAGE)
Isotype:
IgG2b
Storage Buffer:
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Target Reference:
Meraner P, Horejsí V, Wolpl A, Fischer GF, Stingl G, Maurer D: Dendritic cells sensitize TCRs through self-MHC-mediated Src family kinaseactivation. J Immunol. 2007 Feb 15;178(4):2262-71.
Rivera J, Olivera A: A current understanding of Fc epsilon RI-dependent mast cell activation. Curr Allergy Asthma Rep. 2008 Mar;8(1):14-20.
Makinodan E, Manabe T, Makinodan M, Yamauchi T, Matsuyoshi H, Sakumura R, Tatsumi K, Wanaka A. A novel role for Fyn: change in sphere formation ability in murine embryonic stem cells. Neuroscience. 2007 Jun 15;147(1):1-4.
Samayawardhena LA, Kapur R, Craig AW: Involvement of Fyn kinase in Kit and integrin-mediated Rac activation,cytoskeletal reorganization, and chemotaxis of mast cells. Blood. 2007 May 1;109(9):3679-86.
Filby A, Seddon B, Kleczkowska J, Salmond R, Tomlinson P, Smida M, Lindquist JA, Schraven B, Zamoyska R. Fyn regulates the duration of TCR engagement needed for commitment to effector function. J Immunol. 2007 Oct 1;179(7):4635-44.
Wu HY, Hsu FC, Gleichman AJ, Baconguis I, Coulter DA, Lynch DR: Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2Bcleavage in neurons and heterologous systems. J Biol Chem. 2007 Jul 13;282(28):20075-87.
Hattori K, Uchino S, Isosaka T, Maekawa M, Iyo M, Sato T, Kohsaka S, Yagi T, Yuasa S: Fyn is required for haloperidol-induced catalepsy in mice. J Biol Chem. 2006 Mar 17;281(11):7129-35.
Talmor-Cohen A, Tomashov-Matar R, Tsai WB, Kinsey WH, Shalgi R: Fyn kinase-tubulin interaction during meiosis of rat eggs. Reproduction. 2004 Oct;128(4):387-93.
Utting O, Priatel JJ, Teh SJ, Teh HS: p59fyn (Fyn) promotes the survival of anergic CD4-CD8- alpha beta TCR+ cells but negatively regulates their proliferative response to antigen stimulation. J Immunol. 2001 Feb 1;166(3):1540-6.
Protocol:
Tips Information:
 
X
Ask a Question

Tell us what you think about this item!

Write A Review
    Please, wait...