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FBXO7 antibody - middle region (ARP43128_P050)

100 ul

Regular Price: $289.00

Special Price: $215.00

In Stock

Conjugation Options

ARP43128_P050-FITC Conjugated

ARP43128_P050-HRP Conjugated

ARP43128_P050-Biotin Conjugated

Gene Symbol:
FBXO7
NCBI Gene Id:
25793
Official Gene Full Name:
F-box protein 7
Protein Name:
F-box only protein 7
Swissprot Id:
Q9Y3I1
Protein Accession #:
NP_036311
Nucleotide Accession #:
NM_012179
Alias Symbols:
DKFZp686B08113, FBX, FBX07, FBX7, PKPS, PARK15
Replacement Item:
This antibody may replace item sc-271763 from Santa Cruz Biotechnology.
Description of Target:
FBXO7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO7 belongs to the Fbxs class and it may play a role in regulation of hematopoiesis.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
Protein Size (# AA):
522
Molecular Weight:
58kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IP, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express FBXO7.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express FBXO7.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human FBXO7
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 83%; Horse: 92%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 100%; Rat: 93%; Zebrafish: 83%
Complete computational species homology data:
Anti-FBXO7 (ARP43128_P050)
Peptide Sequence:
Synthetic peptide located within the following region: PGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDG
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
PSME3; PSMF1; PSMA3; SKP1; TRAF2; MAGED1; SHFM1; PINK1; PARK2; SEC24C; NEDD8; UBC; COPS5; COPS6; CUL1; BIRC2; RBBP6; XPO1; DLGAP5; ELF4; BIRC3; CDK6; UBE2D2; CDC34;
Blocking Peptide:
For anti-FBXO7 (ARP43128_P050) antibody is Catalog # AAP43128 (Previous Catalog # AAPP25101)
Datasheets/Manuals:
Printable datasheet for anti-FBXO7 (ARP43128_P050) antibody
Sample Type Confirmation:

FBXO7 is supported by BioGPS gene expression data to be expressed in MCF7

Target Reference:
Chang,Y.F., (2006) Biochem. Biophys. Res. Commun. 342 (4), 1022-1026

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