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EXOSC3 antibody - C-terminal region (ARP40230_P050)

100 ul

Regular Price: $289.00

Special Price: $215.00

In Stock

Conjugation Options

ARP40230_P050-FITC Conjugated

ARP40230_P050-HRP Conjugated

ARP40230_P050-Biotin Conjugated

Gene Symbol:
EXOSC3
NCBI Gene Id:
51010
Official Gene Full Name:
Exosome component 3
Protein Name:
Exosome complex component RRP40
Swissprot Id:
Q9NQT5
Protein Accession #:
NP_001002269
Nucleotide Accession #:
NM_001002269
Alias Symbols:
CGI-102, MGC15120, MGC723, RP11-3J10.8, RRP40, Rrp40p, bA3J10.7, hRrp40p, p10, hRrp-40
Replacement Item:
This antibody may replace item sc-107210 from Santa Cruz Biotechnology.
Description of Target:
EXOSC3 is component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA.
Protein Size (# AA):
164
Molecular Weight:
17kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express EXOSC3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express EXOSC3.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human EXOSC3
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 100%
Complete computational species homology data:
Anti-EXOSC3 (ARP40230_P050)
Peptide Sequence:
Synthetic peptide located within the following region: VIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQAISSRL
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; EXOSC5; EXOSC4; CDK5RAP1; EXOSC8; ATP5D; AICDA; EXOSC10; EXOSC9; APP; EXOSC2; EXOSC6; DIS3L; EXOSC1; EXOSC3; EXOSC7; DIS3; MPHOSPH6; HDGF; KHSRP;
Blocking Peptide:
For anti-EXOSC3 (ARP40230_P050) antibody is Catalog # AAP40230 (Previous Catalog # AAPP22074)
Datasheets/Manuals:
Printable datasheet for anti-EXOSC3 (ARP40230_P050) antibody
Target Reference:
Lehner,B. (2004) Genome Res. 14 (7), 1315-1323
Publications:

Fan, M.-J. et al. Reduction of TLR4 mRNA stability and protein expressions through inhibiting cytoplasmic translocation of HuR transcription factor by E₂ and/or ER-alpha in LPS-treated H9c2 cardiomyoblast cells. Chin. J. Physiol. 57, 8-18 (2014). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish 24621334

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