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CDKN1A Antibody - C-terminal region (OAAB09762)

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400ul
$320.00
In Stock
Gene Symbol:
CDKN1A
NCBI Gene Id:
1026
Protein Name:
Cyclin-dependent kinase inhibitor 1
Swissprot Id:
P38936
Protein Accession #:
NP_000380.1
Alias Symbols:
CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1, Cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, Melanoma differentiation-associated protein 6, p21
Replacement Item:
This antibody may replace item sc-271532 from Santa Cruz Biotechnology.
Description of Target:
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Molecular Weight:
18119 Da
Host:
Rabbit
Clonality:
Polyclonal
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Application:
WB, IHC, IF
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CDKN1A.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CDKN1A.
Species Reactivity:
Human, Mouse
Predicted Homology Based on Immunogen Sequence:
Human; Mouse
Product Format:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 6 months. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets / Downloads:
OAAB09762
Specificity:
This CDKN1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-146 amino acids from the C-terminal region of human CDKN1A.
Isotype:
Ig
Intended Use:
CDKN1A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Application Info:
WB 1:1000
IHC 1:10 - 50
IF 1:10 - 50
Additional Information:
Function: May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin- dependent kinase substrates and blocking cell cycle progression Functions in the nuclear localization and assembly of cyclin D- CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex
:::
Cellular Location: Cytoplasm. Nucleus.
Tissue Location: Expressed in all adult tissues, with 5-fold lower levels observed in the brain
Protocol:
Tips Information:

Product Protocol: CDKN1A antibody tested with human Jurkat by western blot (OAAB09762)

Please find the protocol used to generate the western blot data for item (OAAB09762) by going here

Product datasheet link: CDKN1A antibody (OAAB09762)

CDKN1A Antibody (C-term) (Cat. #OAAB09762) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CDKN1A antibody detected the CDKN1A protein (arrow).

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology's CDKN1A antibody (OAAB09762) has been tested using other cell lysates and tissues. To obtain more data about this antibody, please email us at info@avivasysbio.com

To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

All of Aviva's products are guaranteed for the applications and experimental sample types mentioned. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com

Product Protocol: CDKN1A antibody tested with mouse Neuro-2a by western blot (OAAB09762)

Please find the protocol used to generate the western blot data for item (OAAB09762) by going here

Product datasheet link: CDKN1A antibody (OAAB09762)

CDKN1A Antibody (C-term) (Cat. #OAAB09762) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CDKN1A antibody detected the CDKN1A protein (arrow).

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology's CDKN1A antibody (OAAB09762) has been tested using other cell lysates and tissues. To obtain more data about this antibody, please email us at info@avivasysbio.com

To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

All of Aviva's products are guaranteed for the applications and experimental sample types mentioned. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com

Product Protocol: CDKN1A antibody tested with human Breast in immunohistochemistry (IHC) (OAAB09762)

Please go here to see the protocol used for Aviva's CDKN1A antibody (OAAB09762)

Product datasheet can be found here: CDKN1A antibody (OAAB09762)

IHC information:
CDKN1A Antibody (C-term) (Cat. #OAAB09762) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of CDKN1A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology's CDKN1A antibody (OAAB09762) has been tested using other cell lysates and tissues. To obtain more data about this antibody, please email us at info@avivasysbio.com

To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

All of Aviva's products are guaranteed for the applications and experimental sample types mentioned. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com

 
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