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BECN1 Antibody (Ascites) (OAAB06659)

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0.1 ml
$320.00
In Stock
Gene Symbol:
BECN1
NCBI Gene Id:
8678
Protein Name:
Beclin-1
Swissprot Id:
Q14457
Protein Accession #:
NP_003757.1
Alias Symbols:
BECN1, GT197, Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197
Replacement Item:
This antibody may replace item sc-10086, HPA028949
Description of Target:
Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).
Molecular Weight:
51896 Da
Host:
Mouse
Clonality:
Monoclonal
Application:
WB, IHC-P, IF
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express BECN1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express BECN1.
Immunogen:
This BECN1 Monoclonal antibody was raised using purified His-tagged recombinant full length human Autophagy BECN1.
Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human
Product Format:
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Reconstitution and Storage:
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Datasheets / Downloads:
OAAB06659
Clone:
117CT2.5.1.1
Isotype:
IgM,K
Application Info:
WB 1:100~400
IHC-P 1:50~100
IF 1:10~50
Intended Use:
For research use only and not for use in diagnostic or therapeutic procedures.
:::
Function: Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.
Cellular Location: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity)
Tissue Location: Ubiquitous.
Protocol:
Tips Information:

Product Protocol: BECN1 antibody tested with human Jurkat by western blot (OAAB06659)

Please find the protocol used to generate the western blot data for item (OAAB06659) by going here

Product datasheet link: BECN1 antibody (OAAB06659)

Western blot analysis of anti-BECN1 Monoclonal Antibody (Cat. #OAAB06659) in Jurkat cell line lysates (35ug/lane). BECN1 (arrow) was detected using the Mab ascites (1:100 dilution).

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology's BECN1 antibody (OAAB06659) has been tested using other cell lysates and tissues. To obtain more data about this antibody, please email us at info@avivasysbio.com

To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

All of Aviva's products are guaranteed for the applications and experimental sample types mentioned. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com

Product Protocol: BECN1 antibody tested with human Brain in immunohistochemistry (IHC) (OAAB06659)

Please go here to see the protocol used for Aviva's BECN1 antibody (OAAB06659)

Product datasheet can be found here: BECN1 antibody (OAAB06659)

IHC information:
Formalin-fixed and paraffin-embedded human brain with BECN1 Monoclonal Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology's BECN1 antibody (OAAB06659) has been tested using other cell lysates and tissues. To obtain more data about this antibody, please email us at info@avivasysbio.com

To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

All of Aviva's products are guaranteed for the applications and experimental sample types mentioned. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com

 
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