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BCL2L1 Antibody (OAAN00021)

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50ul
    $125.00
    In Stock
    Gene Symbol:
    BCL2L1
    NCBI Gene Id:
    598
    Official Gene Full Name:
    BCL2 like 1
    Protein Name:
    Bcl-2-like protein 1
    Swissprot Id:
    Q07817
    Protein Accession #:
    NP_001182.1
    Nucleotide Accession #:
    NM_001191.3
    Alias Symbols:
    BCL2L1, BCL-XL/S, BCL2L, BCLX, Bcl-X, DKFZp781P2092, bcl-xL, bcl-xS, BCLXS, BCLX, BCL2L, Bcl-X, PPP1R52, BCL-XL/S, BCL2 like 1, Bcl-2-like protein 1, BCL2L1
    Description of Target:
    The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
    Molecular Weight:
    26 kDa
    Host:
    Rabbit
    Clonality:
    Polyclonal
    Purification:
    Affinity purified against immunogen
    Application:
    WB, IHC, IF, IP
    Tissue Tool:
    Find tissues and cell lines supported by DNA array analysis to express BCL2L1.
    RNA Seq:
    Find tissues and cell lines supported by RNA-seq analysis to express BCL2L1.
    Immunogen:
    Recombinant protein of human BCL2L1
    Species Reactivity:
    Human, Mouse, Rat
    Product Format:
    Liquid
    Reconstitution and Storage:
    Store at -20C. Avoid repeated freeze/thaw cycles.
    Datasheets / Downloads:
    Printable datasheet for anti-BCL2L1 (OAAN00021)
    Preservative:
    0.02% Sodium Azide
    Conjugation:
    Unconjugated
    Isotype:
    IgG
    Application Info:
    WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200. IP: 1:20 - 1:50
    Storage Buffer:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    Protocol:
    Tips Information:
     
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