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BCL2L1 Antibody (OAAN00021)

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Gene Symbol:
BCL2L1
NCBI Gene Id:
598
Official Gene Full Name:
BCL2 like 1
Protein Name:
Bcl-2-like protein 1
Swissprot Id:
Q07817
Protein Accession #:
NP_001182.1
Nucleotide Accession #:
NM_001191.3
Alias Symbols:
BCL2L1, BCL-XL/S, BCL2L, BCLX, Bcl-X, DKFZp781P2092, bcl-xL, bcl-xS, BCLXS, BCLX, BCL2L, Bcl-X, PPP1R52, BCL-XL/S, BCL2 like 1, Bcl-2-like protein 1, BCL2L1
Description of Target:
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Molecular Weight:
26 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified against immunogen
Application:
WB, IHC, IF, IP
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express BCL2L1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express BCL2L1.
Immunogen:
Recombinant protein of human BCL2L1
Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Datasheets/Manuals:
Printable datasheet for anti-BCL2L1 (OAAN00021)
Preservative:
0.02% Sodium Azide
Conjugation:
Unconjugated
Isotype:
IgG
Application Info:
WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200. IP: 1:20 - 1:50
Storage Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Protocol:
Tips Information:

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