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Anti-OCT-2 Antibody (OAAI00239)

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100 ug
$250.00
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Gene Symbol:
RB1
NCBI Gene Id:
5925
Official Gene Full Name:
retinoblastoma 1
Swissprot Id:
P06400
Alias Symbols:
RB, pRb, OSRC, pp110, p105-Rb, PPP1R130,
Replacement Item:
This antibody may replace item sc-102 from Santa Cruz Biotechnology.
Description of Target:
Oct1 and Oct2 are transcription factors of the POU homeo-domain family that bind to the lg gene octamer sites, regulating B-cell-specific genes. The function of these transcription factors is dependent on the activity of B-cell-restricted coactivators such as BOB.1/OBF.1.Absence of functional Oct-2 and Bob-1 cells represents a novel mechanism for immunoglobulin gene deregulation
Molecular Weight:
55 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
The Rabbit IgG is purified by Epitope Affinity Purification.
Application:
IHC, WB, IP
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express RB1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RB1.
Immunogen:
A synthetic peptide corresponding to C-terminus of OCT-2 protein from Human, Mouse and Rat origins.
Species Reactivity:
Human, Mouse, Rat
Reconstitution and Storage:
The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity.
Avoid repeated freezing thawing cycles.
Datasheets / Downloads:
Printable datasheet for Rabbit Anti-OCT-2 Antibody OAAI00239
Specificity:
This antibody recognizes ~55 kDa of OCT-2 protein from Human, Rat and Mouse origins. It does not cross react with OCT-1, OCT-4. The other species are not tested
Isotype:
Rabbit IgG
Application Info:
Positive Control: Jurkat Cell Lysate
Western Blot: 0.1-1 μg/ml
ELISA: 0.01-0.1 μg/ml
IP: 2-5 μg/ml
IHC: 0.5-2 μg/ml
Target Reference:
Daniel Re, et al. Oct-2 and Bob-1 Deficiency in Hodgkin and Reed Sternberg Cells. Cancer Research 61, 2080-2084 (2001).
Protocol:
Tips Information:
 
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