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Anti-12(L)-HETE Antibody (OAED00005)

100 ul
$285.00
In Stock
Gene Symbol:
12(L)-HETE
Description of Target:
HETEs are byproducts generated by the metabolism of arachidonic acid by lipoxygenases. 12(S)-HETE is the stereospecific hydroxy product from the reduction of 12(S)-hydroperoxy tetraenoic eicosatetraenoic acid [12(S)-HpETE], which itself is a 12-lipoxygenase metabolite of arachidonic acid. 12(S)-HETE is chemotactic and chemokinetic for polymorphonuclear leukocytes and vascular smooth muscle cells. It also acts as a second messenger in angiotensin-II induced aldosterone production. 15-hydroxyeicosatetraenoic acid [15(S)-HETE] is the major hydroxy derivative of arachidonic acid when acted upon by 15-lipoxygenase. It is also the primary monohydroxy acid synthesized by the lipoxygenase activity of Cyclooxygenase-1 upon linoleic acid. 15(S)-HETE acts as a paracrine regulator of smooth muscle and lung neutrophil recrui™ent, and elevated levels of 15(S)-HETE are associated with asthma, rhinitis, chronic paranasal sinusitis and rheumatoid arthritis.
Host:
Rabbit
Clonality:
Polyclonal
Application:
ELISA
Immunogen:
12(S)-HETE conjugated to human serum albumin.
Reconstitution and Storage:
Long Term Storage : -20C
Datasheets/Manuals:
Printable datasheet for Anti-12(L)-HETE Antibody (OAED00005)OAED00005
Specificity:
Species independent.
Formulation:
Liquid. Contains sodium azide.
Application Info:
ELISA
Optimal conditions must be determined individually for each application.
Protocol:
Tips Information:

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