Now Offering Over 102,157 Antibodies & 44,722 Antigens!

ADORA3 antibody - C-terminal region (ARP59956_P050)

100 ul

Regular Price: $289.00

Special Price: $215.00

In Stock

Conjugation Options

ARP59956_P050-FITC Conjugated

ARP59956_P050-HRP Conjugated

ARP59956_P050-Biotin Conjugated

Gene Symbol:
ADORA3
NCBI Gene Id:
140
Official Gene Full Name:
Adenosine A3 receptor
Protein Name:
Protein ADORA3, isoform 3
Swissprot Id:
Q5QNY7
Protein Accession #:
NP_001075445
Nucleotide Accession #:
NM_001081976
Alias Symbols:
A3AR, AD026, bA552M11.5, RP11-552M11.7
Replacement Item:
This antibody may replace item sc-115823 from Santa Cruz Biotechnology.
Description of Target:
This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Size (# AA):
266
Molecular Weight:
30kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ADORA3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ADORA3.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA3
Species Reactivity:
Cow, Horse, Human, Pig, Rabbit
Predicted Homology Based on Immunogen Sequence:
Cow: 75%; Horse: 93%; Human: 100%; Pig: 85%; Rabbit: 77%
Complete computational species homology data:
Anti-ADORA3 (ARP59956_P050)
Peptide Sequence:
Synthetic peptide located within the following region: RSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQRNRRV
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
YWHAQ; YWHAZ;
Blocking Peptide:
For anti-ADORA3 (ARP59956_P050) antibody is Catalog # AAP59956 (Previous Catalog # AAPP46118)
Datasheets/Manuals:
Printable datasheet for anti-ADORA3 (ARP59956_P050) antibody
Publications:

Merighi, S. et al. Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells. Mol. Pharmacol. 72, 162-72 (2007). IHC, WB, Cow, Horse, Human, Pig, Rabbit 17400763

Tell us what you think about this item!

Write A Review
    Please, wait...