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EML1 Antibody (OAGA00029)

100 ul
$329.00
In Stock
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Predicted Species Reactivity:
Human, Mouse
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
ICC, IF, IHC-FFPE, WB
Additional Information:
Background: Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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Positive Controls: H1299, NIH-3T3
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Cellular Localization: Cytoplasm
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item:
This antibody may replace item sc-144642 from Santa Cruz Biotechnology.
Immunogen:
Synthetic peptide corresponding to a region within amino acids 753 and 815 of EML1 (Uniprot ID#O00423)
Purification:
Purified by antigen-affinity chromatography.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-EML1 antibody - OAGA00029
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol:
EML1
Official Gene Full Name:
Echinoderm microtubule-associated protein-like 1
Alias Symbols:
ELP79 antibody, EMAP antibody, EMAPL antibody, FLJ45033 antibody, HuEMAP antibody, EML1 antibody, huEMAP-1 antibody, echinoderm microtubule-associated protein-like 1 antibody, EMAP-1 antibody, echinoderm microtubule associated protein like 1 antibody
NCBI Gene Id:
2009
Protein Name:
Echinoderm microtubule-associated protein-like 1
Swissprot Id:
O00423
Protein Accession #:
NP_001008707.1
Molecular Weight:
92 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express EML1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express EML1.

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