Emetine (OOMC00054)

Catalog No: OOMC00054

Product Info

• Product Format: Lyophilized
• Additional Information: Molecular Formula: C₂₉H₄₀N₂O₄ · 2HCl (XH₂O)
  Chemical Name: (2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-2H-benzo[a]quinolizine, dihydrochloride, hydrate
• Reconstitution and Storage: May be dissolved in water (100 mg/ml). Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 3 months.
• Purity: > 98% (TLC); NMR (Conforms)

Target Info

• Description of Target: One of the active ingredients of ipecac root extract, used as an emetic. Induces apoptosis in breast cancer cells via inhibition of Wnt/beta-catenin signaling. Inhibits Zika and Ebola virus in vitro and in vivo, targeting viral entry and replication by inhibiting viral RNA polymerase and host lysosomal function. Also inhibits SARS-CoV-2 replication in cells (EC₅₀ for viral load reduction is 0.46 uM). A useful agent for inhibiting protein synthesis in eukaryotic cells by virtue of its inhibition of the ribosome 40S subunit.
• Molecular Weight: 553.6 g/mol