ELOVL5 Antibody (OAAF03639)

Catalog No: OAAF03639 (Formerly GWB-ASE579)

Size:100 ug

Western blot analysis of extracts from MCF-7 cells, using ELOVL5 Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ELOVL5 Antibody. The picture on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human ELOVL5.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: ELOVL5 antibody detects endogenous levels of total ELOVL5 protein.
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:40000
• Reference: Leonard A.E., Biochem. J. 350:765-770(2000).
  Suzuki T., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
  Wiemann S., Genome Res. 11:422-435(2001).

Target Info

• Gene Symbol: ELOVL5
• Gene Full Name: ELOVL fatty acid elongase 5
• Alias Symbols: 3-keto acyl-CoA synthase ELOVL5;dJ483K16.1;elongation of very long chain fatty acids protein 5;ELOVL FA elongase 5;ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast);ELOVL fatty acid elongase 5;fatty acid elongase 1;HELO1;homolog of yeast long chain polyunsaturated fatty acid elongation enzyme 2;SCA38;spinocerebellar ataxia 38;very long chain 3-ketoacyl-CoA synthase 5;very long chain 3-oxoacyl-CoA synthase 5.
• NCBI Gene Id: 60481
• Protein Name: Elongation of very long chain fatty acids protein 5
• Description of Target: Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
• Uniprot ID: Q9NYP7
• Protein Accession #: NP_001229757.1
• Molecular Weight: 35 kDa