Catalog No: OPCA00236
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ELOC Recombinant Protein (Human) (OPCA00236)

Datasheets/ManualsPrintable datasheet for ELOC Recombinant Protein (Human) (OPCA00236) (OPCA00236)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatLiquid or Lyophilized powder
Additional Information Tag information : GST tag
Reconstitution and Storage-20°C or -80°C
PurityGreater than 90% as determined by SDS-PAGE.
Storage BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Protein Range1-112 aa
TagN-terminal GST-tagged
ReferenceStructure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation.Bullock A.N., Rodriguez M.C., Debreczeni J.E., Songyang Z., Knapp S.Structure 15:1493-1504(2007)
Gene SymbolELOC
Gene Full Nameelongin C
Alias Symbolselongin 15 kDa subunit;elongin-C;RNA polymerase II transcription factor SIII subunit C;SIII;SIII p15;TCEB1;transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C);transcription elongation factor B polypeptide 1;transcription elongation factor B subunit 1.
NCBI Gene Id6921
Protein NameElongin-C
Description of TargetSIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (PubMed:7821821). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells (By similarity).
Uniprot IDQ15369
Protein Size (# AA)Recombinant
Molecular Weight39.5 kDa
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