ELOA2 Antibody - middle region (ARP35916_P050)

Catalog No: ARP35916_P050

WB Suggested Anti-TCEB3B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: OVCAR-3 cell lysateTCEB3B is supported by BioGPS gene expression data to be expressed in OVCAR3

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TCEB3B
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human: 100%
• Peptide Sequence: Synthetic peptide located within the following region: QAGSGQRVPALEEAPDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEE
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-ELOA2 (ARP35916_P050) antibody is Catalog # AAP35916 (Previous Catalog # AAPP08907)
• Sample Type Confirmation:

  TCEB3B is supported by BioGPS gene expression data to be expressed in OVCAR3

• Subunit: A2
• Reference: Lim,J., (2006) Cell 125 (4), 801-814

Target Info

• Gene Symbol: ELOA2
• Gene Full Name: elongin A2
• Alias Symbols: HsT832, TCEB3B, TCEB3L
• NCBI Gene Id: 51224
• Protein Name: elongin-A2
• Description of Target: This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.
• Uniprot ID: Q8IYF1
• Protein Accession #: NP_057511
• Nucleotide Accession #: NM_016427
• Protein Size (# AA): 753
• Molecular Weight: 84kDa
• Protein Interactions: ZCCHC10; HECW2; CDK6; COIL; TCEB2; TCEB1; CEP70; KXD1; KRTAP4-12; ZBTB43; SOHLH2; CALCOCO2; TRIM37; CBX5; DVL2; TRAF2; ZNF165;