ELMO2 Antibody - middle region (OAAB07346)

Catalog No: OAAB07346

Size:400ul

ELMO2 Antibody (Center) (Cat. #OAAB07346) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ELMO2 antibody detected the ELMO2 protein (arrow).

There is BioGPS gene expression data showing that ELMO2 is expressed in Jurkat

ELMO2 Antibody (Center) (Cat. #OAAB07346)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ELMO2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

ELMO2 Antibody (Center) (Cat. #OAAB07346) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human, Mouse, Cow
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC, FC
• Additional Information: Precautions: ELMO2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1
  Cellular Location: Cytoplasm. Cytoplasm, cytosol. Membrane.
  Tissue Location: Widely expressed, with a higher expression in skeletal muscle, kidney and placenta
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This ELMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-350 amino acids from the Central region of human ELMO2.
• Predicted Homology Based on Immunogen Sequence: Cow; Human; Mouse
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that ELMO2 is expressed in Jurkat

• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50

Target Info

• Gene Symbol: ELMO2
• Alias Symbols: VMPI, CED12, CED-12, ELMO-2, Ced-12A
• NCBI Gene Id: 63916
• Protein Name: Engulfment and cell motility protein 2
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q96JJ3
• Protein Accession #: NP_573403.1
• Molecular Weight: 82615 Da