EIF4G1 Antibody - middle region (ARP40562_P050)

Catalog No: ARP40562_P050

WB Suggested Anti-EIF4G1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: HepG2 cell lysateEIF4G1 is supported by BioGPS gene expression data to be expressed in HepG2

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EIF4G1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 79%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%
• Peptide Sequence: Synthetic peptide located within the following region: PAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQ
• Concentration: 0.5 mg/ml
• Blocking Peptide: Catalog # AAP40562 (Previous Catalog # AAPP22322)
• Sample Type Confirmation:

  EIF4G1 is supported by BioGPS gene expression data to be expressed in HepG2

• Reference: Petersen,K.E., (2008) J. Cell Biol. 181 (2), 293-307

Target Info

• Gene Symbol: EIF4G1
• Gene Full Name: Eukaryotic translation initiation factor 4 gamma, 1
• Alias Symbols: P220, EIF4F, EIF4G, EIF4GI, PARK18, EIF-4G1
• NCBI Gene Id: 1981
• Protein Name: Eukaryotic translation initiation factor 4 gamma 1
• Description of Target: EIF4G1 is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure, and recruitment of mRNA to the ribosome.The protein encoded by this gene is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure, and recruitment of mRNA to the ribosome. Alternative splicing results in five transcript variants encoding four distinct isoforms.
• Uniprot ID: Q04637
• Protein Accession #: NP_886553
• Nucleotide Accession #: NM_182917
• Protein Size (# AA): 1599
• Molecular Weight: 175kDa
• Protein Interactions: POLDIP3; EIF4E; UBC; NCBP1; SUMO1; SUMO2; MDM2; LGR4; AIMP1; IQGAP1; EEF1E1; AIMP2; QARS; PTBP1; PSMB8; TARDBP; UBD; BRCA1; ITGA4; GK; FN1; HTRA2; ZFYVE9; VCAM1; HNRNPD; ESR1; EIF4G3; FTL; EIF4G2; RAB31; SF3A3; EIF4B; EIF4A1; TRAF2; CUL3; ISG15; YWHAZ; SI