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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for OAAQ00048 |
|---|
| Tested Species Reactivity | Human, Mouse, Rat |
|---|---|
| Predicted Species Reactivity | Mouse, Rat |
| Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
| Clonality | Monoclonal |
| Clone | 4EB1T37T46-A5 |
| Isotype | Rabbit IgG1k |
| Host | Rabbit |
| Conjugation | FITC: Fluorescein Isothiocyanate |
| Application | FC |
| Reconstitution and Storage | 2-8C |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1 |
| Purification | Protein A+G |
| Target Post-Translational Modification | Phospho-Thr37/46 |
| Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Reference | Hay N. Sonenberg N, (2004) Gens Dev. 18: 1926-1945. Aitken CE, and Lorsch JR, (2012), Nat Struc Mol Biol 19 : 568-576. Peter D., et al., (2015) Mol Cell, 57:1074-1087. Pain VM, (1996) Eur J Biochem 236: 747-771. Fadden P, Haystead TA, Lawrence Jr JC, (1997) J Biol Chem 272: 10240-10247. Kimball SR et al., (1999) J Biol Chem 274: 11647-1152. Kleijn M and Proud CG, (2000) Biochem J, 347: 399-406. Lang CH et al., (2000) Clin Exp Res 24: 322-331. Shah OJ, Kimbell SR., Jefferson LS., (2000), Am J Physiol Endocrinol Metab 278: E76-E82. |
| Gene Symbol | EIF4EBP1 |
|---|---|
| Gene Full Name | eukaryotic translation initiation factor 4E binding protein 1 |
| Alias Symbols | BP-1, 4EBP1, 4E-BP1, PHAS-I |
| NCBI Gene Id | 1978 |
| Protein Name | eukaryotic translation initiation factor 4E-binding protein 1 |
| Description of Target | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. |
| Uniprot ID | Q13541 |
| Protein Accession # | NP_004086.1 |
| Nucleotide Accession # | NM_004095.3 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Human EIF4EBP1 Antibody : FITC (Phospho-Thr37/46) (OAAQ00048)"?
The tested species reactivity for this item is "Human, Mouse, Rat". This antibody is predicted to have homology to "Mouse, Rat".
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How long will it take to receive "Human EIF4EBP1 Antibody : FITC (Phospho-Thr37/46) (OAAQ00048)"?
This item is available "Domestic: within 1 week delivery | International: 1 week".
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What buffer format is "Human EIF4EBP1 Antibody : FITC (Phospho-Thr37/46) (OAAQ00048)" provided in?
This item is provided in "Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Human EIF4EBP1 Antibody : FITC (Phospho-Thr37/46) (OAAQ00048)"?
This target may also be called "BP-1, 4EBP1, 4E-BP1, PHAS-I" in publications.
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What is the shipping cost for "Human EIF4EBP1 Antibody : FITC (Phospho-Thr37/46) (OAAQ00048)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Human EIF4EBP1 Antibody : FITC (Phospho-Thr37/46) (OAAQ00048)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Human EIF4EBP1 Antibody : FITC (Phospho-Thr37/46) (OAAQ00048)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Human EIF4EBP1 Antibody : FITC (Phospho-Thr37/46) (OAAQ00048)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "EIF4EBP1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "EIF4EBP1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "EIF4EBP1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "EIF4EBP1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "EIF4EBP1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "EIF4EBP1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
