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EIF4E3 antibody - middle region (ARP41168_P050)

100 ul
$319.00
In Stock
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Conjugation Options

ARP41168_P050-FITC Conjugated

ARP41168_P050-HRP Conjugated

ARP41168_P050-Biotin Conjugated

Gene Symbol:
EIF4E3
NCBI Gene Id:
317649
Official Gene Full Name:
Eukaryotic translation initiation factor 4E family member 3
Protein Name:
Eukaryotic translation initiation factor 4E type 3
Swissprot Id:
Q8N5X7
Protein Accession #:
NP_001128123
Nucleotide Accession #:
NM_001134649
Alias Symbols:
MGC39820, MGC86971
Replacement Item:
This antibody may replace item sc-133542 from Santa Cruz Biotechnology.
Description of Target:
EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome.
Protein Size (# AA):
224
Molecular Weight:
24kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express EIF4E3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express EIF4E3.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human EIF4E3
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data:
Anti-EIF4E3 (ARP41168_P050)
Peptide Sequence:
Synthetic peptide located within the following region: VQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
ELAVL1; DCC;
Blocking Peptide:
For anti-EIF4E3 (ARP41168_P050) antibody is Catalog # AAP41168 (Previous Catalog # AAPP22543)
Datasheets/Manuals:
Printable datasheet for anti-EIF4E3 (ARP41168_P050) antibody
Publications:

Yi, T., Papadopoulos, E., Hagner, P. R. & Wagner, G. Hypoxia-inducible factor-1-alpha (HIF-1-alpha) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions. J. Biol. Chem. 288, 18732-42 (2013). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 23667251

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