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EIF2B2 Antibody (OAGA01031)

100 ul
$329.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
IHC-FFPE, WB
Additional Information:
Background: Eukaryotic initiation factor-2B (EIF2B) is a GTP exchange protein essential for protein synthesis. It consists of alpha (EIF2B1; MIM 606686), beta (EIF2B2), gamma (EIF2B3; MIM 606273), delta (EIF2B4; MIM 606687), and epsilon (EIF2B5; MIM 603945) subunits. EIF2B activates its EIF2 (see MIM 603907) substrate by exchanging EIF2-bound GDP for GTP.[supplied by OMIM]
:::
Positive Controls: 293T, A431, HeLa, HepG2, Molt-4, Raji
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item:
This antibody may replace item sc-100729 from Santa Cruz Biotechnology.
Immunogen:
Recombinant fragment corresponding to a region within amino acids 88 and 323 of EIF2B beta (Uniprot ID#P49770)
Purification:
Purified by antigen-affinity chromatography.
Concentration:
0.43 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-EIF2B2 antibody - OAGA01031
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol:
EIF2B2
Official Gene Full Name:
Translation initiation factor eIF-2B subunit beta
Alias Symbols:
EIF-2Bbeta antibody, EIF2B antibody, EIF2B2 antibody, S20I15 antibody, translation initiation factor eIF-2B subunit beta antibody, eIF-2B GDP-GTP exchange factor subunit beta antibody, S20III15 antibody, "eukaryotic translation initiation factor 2B, subun
NCBI Gene Id:
8892
Protein Name:
Translation initiation factor eIF-2B subunit beta
Swissprot Id:
P49770
Protein Accession #:
NP_055054.1
Molecular Weight:
39 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express EIF2B2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express EIF2B2.

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