EIF2B1 Antibody - C-terminal region (ARP51963_P050)

Catalog No: ARP51963_P050

WB Suggested Anti-EIF2B1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateEIF2B1 is supported by BioGPS gene expression data to be expressed in Jurkat

Rabbit Anti-EIF2B1 Antibody
Catalog Number: ARP51963_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: N/A
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2B1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 79%; Dog: 79%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 79%; Rabbit: 79%; Rat: 79%
• Peptide Sequence: Synthetic peptide located within the following region: ADTLKVAQTGQDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKL
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-EIF2B1 (ARP51963_P050) antibody is Catalog # AAP51963 (Previous Catalog # AAPY03609)
• Sample Type Confirmation:

  EIF2B1 is supported by BioGPS gene expression data to be expressed in Jurkat

• Subunit: alpha
• Reference: Maletkovic,J., (2008) J. Child Neurol. 23 (2), 205-215

Target Info

• Gene Symbol: EIF2B1
• Gene Full Name: Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
• Alias Symbols: EIF2B, EIF2BA
• NCBI Gene Id: 1967
• Protein Name: Translation initiation factor eIF-2B subunit alpha
• Description of Target: EIF2B1 belongs to the EIF-2B alpha/beta/delta subunits family. It catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Defects in EIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM).
• Uniprot ID: Q14232
• Protein Accession #: NP_001405
• Nucleotide Accession #: NM_001414
• Protein Size (# AA): 305
• Molecular Weight: 34kDa
• Protein Interactions: RD3; WDYHV1; GORASP2; EIF2B1; UBC; GCD2; GCD6; EIF2B2; STK11; DCC; MRPL4; EIF2S2; EIF2S1; ARL4D; CREBBP; ADRB2; ADRA2B; ADRA2C; ADRA2A; EIF2B5; DCD; PDIA4; EIF2B3; HNRNPL; ARHGDIA;