EIF2AK2 Antibody - middle region (ARP36709_P050)

Catalog No: ARP36709_P050

WB Suggested Anti-EIF2AK2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Hela cell lysateEIF2AK2 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EIF2AK2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 92%; Dog: 83%; Horse: 91%; Human: 100%; Mouse: 83%; Pig: 83%; Rabbit: 100%; Rat: 92%
• Peptide Sequence: Synthetic peptide located within the following region: QVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDG
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-EIF2AK2 (ARP36709_P050) antibody is Catalog # AAP36709 (Previous Catalog # AAPP08602)
• Sample Type Confirmation:

  EIF2AK2 is strongly supported by BioGPS gene expression data to be expressed in HeLa

Target Info

• Gene Symbol: EIF2AK2
• Gene Full Name: Eukaryotic translation initiation factor 2-alpha kinase 2
• Alias Symbols: PKR, PRKR, LEUDEN, EIF2AK1, PPP1R83
• NCBI Gene Id: 5610
• Protein Name: Interferon-induced, double-stranded RNA-activated protein kinase
• Description of Target: EIF2AK2 might play a role in ER stress-induced apoptosis and in Alzheimer's disease. Alzheimer cases show prominent EIF2AK2 activation in association with neuritic plaques and pyramidal neurons in the hippocampus and neocortex.
• Uniprot ID: P19525
• Protein Accession #: NP_002750
• Nucleotide Accession #: NM_002759
• Protein Size (# AA): 551
• Molecular Weight: 62kDa
• Protein Interactions: UBC; TRAF6; TRAF5; TRAF2; EGFR; DHX9; STAU2; PRKRA; EIF2AK2; HECW2; TOP1; STAU1; DICER1; DHX30; EBNA1BP2; IGF2BP2; IGF2BP3; PABPC4; MOV10; ILF3; ILF2; HSP90AA1; EIF2A; NOC3L; GNL3; NOP2; HNRNPC; HIST1H1C; ELAVL1; NPM1; IL7R; gag; Jak2; TYK2; JAK1; EIF2S1;