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Catalog No: ARP42405_P050-FITC
Size:100ul
Price: $434.00
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ARP42405_P050-FITC
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EIF2AK1 Antibody - N-terminal region : FITC (ARP42405_P050-FITC)

Datasheets/ManualsPrintable datasheet for anti-EIF2AK1 (ARP42405_P050-FITC) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationFITC: Fluorescein Isothiocyanate
ApplicationWB, IHC
Additional InformationIHC Information: Brain, cerebellum
IHC Information: Lung
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human EIF2AK1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Peptide SequenceSynthetic peptide located within the following region: TCSDEFSSLRLHHNRAITHLMRSAKERVRQDPCEDISRIQKIRSREVALE
Concentration0.5 mg/ml
Blocking PeptideFor anti-EIF2AK1 (ARP42405_P050-FITC) antibody is Catalog # AAP42405 (Previous Catalog # AAPP11557)
Sample Type Confirmation

EIF2AK1 is strongly supported by BioGPS gene expression data to be expressed in HEK293T, HeLa

ReferenceOlsen,J.V., (2006) Cell 127 (3), 635-648
Gene SymbolEIF2AK1
Gene Full NameEukaryotic translation initiation factor 2-alpha kinase 1
Alias SymbolsHCR, HRI, hHRI, LEMSPAD
NCBI Gene Id27102
Protein NameEukaryotic translation initiation factor 2-alpha kinase 1
Description of TargetEIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.The HRI gene is localized to 7p22 where its 3' end slightly overlaps the 3' end of the gene JTV1. The two genes are transcribed from opposite strands. Studies in rat and rabbit suggest that the HRI gene product phosphorylates the alpha subunit of eukaryotic initiation factor 2. Its kinase activity is induced by low levels of heme and inhibited by the presence of heme. Sequence Note: The sequence AF181071.1 is a chimeric mRNA clone. Only the heme-regulated initiation factor 2-alpha kinase region was propagated into this RefSeq record.
Uniprot IDQ9BQI3
Protein Accession #NP_055228
Nucleotide Accession #NM_014413
Protein Size (# AA)630
Molecular Weight71kDa
Protein InteractionsMDM2; UBC; HSP90AA1; LIG4; CDC37; EIF2AK1; EIF2S1;
  1. What is the species homology for "EIF2AK1 Antibody - N-terminal region : FITC (ARP42405_P050-FITC)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "EIF2AK1 Antibody - N-terminal region : FITC (ARP42405_P050-FITC)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "EIF2AK1 Antibody - N-terminal region : FITC (ARP42405_P050-FITC)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "EIF2AK1 Antibody - N-terminal region : FITC (ARP42405_P050-FITC)"?

    This target may also be called "HCR, HRI, hHRI, LEMSPAD" in publications.

  5. What is the shipping cost for "EIF2AK1 Antibody - N-terminal region : FITC (ARP42405_P050-FITC)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "EIF2AK1 Antibody - N-terminal region : FITC (ARP42405_P050-FITC)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "EIF2AK1 Antibody - N-terminal region : FITC (ARP42405_P050-FITC)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "71kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "EIF2AK1 Antibody - N-terminal region : FITC (ARP42405_P050-FITC)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "EIF2AK1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "EIF2AK1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "EIF2AK1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "EIF2AK1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "EIF2AK1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "EIF2AK1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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