EFNB2 Recombinant Protein (OPCD02858)

Catalog No: OPCD02858

EFNB2 Recombinant Protein (OPCD02858) using SDS-PAGE

EFNB2 Recombinant Protein (OPCD02858) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Phe42-Val333
  Subcellular Location: Membrane
  Isoelectric Point: 8.7
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: EFNB2
• Gene Full Name: ephrin B2
• Alias Symbols: eph-related receptor tyrosine kinase ligand 5;ephrin-B2;EPLG5;HTK ligand;Htk-L;HTKL;LERK5;ligand of eph-related kinase 5.
• NCBI Gene Id: 1948
• Protein Name: Ephrin-B2
• Description of Target: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
• Uniprot ID: P52799
• Protein Accession #: NP_004084.1
• Nucleotide Accession #: NM_004093.3
• Protein Size (# AA): Phe42~Val333
• Molecular Weight: 38kDa