EFNB1 Antibody (OAAJ07455)

Catalog No: OAAJ07455

Size:100 uL

Western blot analysis of extracts of various celllines, using EFNB1 antibody.

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
• Immunogen: A synthetic peptide of human EFNB1
• Purification: Immunogen affinity chromatography
• Concentration: 1 mg/mL

Target Info

• Gene Symbol: EFNB1
• Alias Symbols: CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2
• NCBI Gene Id: 1947
• Protein Name: Ephrin-B1
• Description of Target: Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons . Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons .
• Uniprot ID: P98172
• Protein Accession #: NP_004420
• Nucleotide Accession #: NM_004429
• Molecular Weight: 38 kDa