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EFEMP1 Antibody - middle region (ARP41342_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP41342_P050-FITC Conjugated

ARP41342_P050-HRP Conjugated

ARP41342_P050-Biotin Conjugated

Tested Species Reactivity:
Human
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality:
Polyclonal
Host:
Rabbit
Application:
WB
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
EFEMP1
Official Gene Full Name:
EGF containing fibulin-like extracellular matrix protein 1
NCBI Gene Id:
2202
Protein Name:
EGF-containing fibulin-like extracellular matrix protein 1
Swissprot Id:
Q12805
Protein Accession #:
NP_004096
Nucleotide Accession #:
NM_004105
Alias Symbols:
DHRD, DRAD, FBLN3, FBNL, FLJ35535, MGC111353, MLVT, MTLV, S1-5
Replacement Item:
This antibody may replace item sc-33722 from Santa Cruz Biotechnology.
Description of Target:
EFEMP1 gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy.This gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy.
Protein Size (# AA):
493
Molecular Weight:
53kDa
Purification:
Affinity Purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express EFEMP1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express EFEMP1.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human EFEMP1
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Complete computational species homology data:
Anti-EFEMP1 (ARP41342_P050)
Peptide Sequence:
Synthetic peptide located within the following region: KYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPV
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
TXNDC5; RIC8A; BAG6; TRAF2; SGTA; env; HCVgp1; KHDRBS1; TNIP1; SOCS6; UBC; PDIA3; NOS3; GFI1B; ATN1; RERE; ATXN7; CACNA1A; ARAF; TIMP3; RAF1;
Blocking Peptide:
For anti-EFEMP1 (ARP41342_P050) antibody is Catalog # AAP41342 (Previous Catalog # AAPP22613)
Datasheets/Manuals:
Printable datasheet for anti-EFEMP1 (ARP41342_P050) antibody
Target Reference:
Weedon,M.N., (2008) Nat. Genet. 40 (5), 575-583
Publications:

Lutter, S., Xie, S., Tatin, F. & Makinen, T. Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation. J. Cell Biol. 197, 837-49 (2012). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish 22665518

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