Catalog No: ARP35696_P050-HRP
Size:100ul
Price: $434.00
SKU
ARP35696_P050-HRP
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Eed Antibody - N-terminal region : HRP (ARP35696_P050-HRP)

Datasheets/ManualsPrintable datasheet for anti-Eed (ARP35696_P050-HRP) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityPolyclonal
HostRabbit
ConjugationHRP: Horseradish Peroxidase
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Peptide SequenceSynthetic peptide located within the following region: AKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKS
Concentration0.5 mg/ml
Blocking PeptideFor anti-Eed (ARP35696_P050-HRP) antibody is Catalog # AAP35696
Gene SymbolEed
Gene Full NameEmbryonic ectoderm development
Alias Symbolsl7, l(7), lusk, l7Rn5, l(7)5Rn
NCBI Gene Id13626
Protein NamePolycomb protein EED
Description of TargetEed is a polycomb group (PcG) protein. It is a component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8. Eed plays a role in X chromosome inactivation (XCI), in which one of the two X chromosomes in female mammals is transcriptionally silenced to equalize X-linked gene dosage with XY males. Eed is required for stable maintenance of XCI in both embryonic and extra-embryonic tissues. Eed may prevent transcriptional activation of facultative heterochromatin during differentiation. Eed is required for development of secondary trophoblast giant cells during placental development. Eed may regulate hippocampal synaptic plasticity in the developing brain.
Uniprot IDQ921E6
Protein Accession #NP_068676
Nucleotide Accession #NM_021876
Protein Size (# AA)441
Molecular Weight50kDa
Protein InteractionsEzh2; Suz12; Rab3gap1; Ddx47; Nop10; Nip7; Bola2; Tmem14c; Uqcr10; Eif3f; Cbwd1; Smc5; Etf1; Svil; Fbxo11; Srsf7; Safb; Safb2; Abcf1; Bag6; C330027C09Rik; Pak2; Pphln1; Ttll12; Sun2; Tomm22; Eif3l; E430025E21Rik; Eny2; Dcaf13; Trio; Ccar2; Fermt2; Vps41;
  1. What is the species homology for "Eed Antibody - N-terminal region : HRP (ARP35696_P050-HRP)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "Eed Antibody - N-terminal region : HRP (ARP35696_P050-HRP)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "Eed Antibody - N-terminal region : HRP (ARP35696_P050-HRP)" provided in?

    This item is provided in "Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Eed Antibody - N-terminal region : HRP (ARP35696_P050-HRP)"?

    This target may also be called "l7, l(7), lusk, l7Rn5, l(7)5Rn" in publications.

  5. What is the shipping cost for "Eed Antibody - N-terminal region : HRP (ARP35696_P050-HRP)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Eed Antibody - N-terminal region : HRP (ARP35696_P050-HRP)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Eed Antibody - N-terminal region : HRP (ARP35696_P050-HRP)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "50kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Eed Antibody - N-terminal region : HRP (ARP35696_P050-HRP)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "EED"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "EED"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "EED"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "EED"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "EED"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "EED"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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