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Now Offering Over 102,157 Antibodies & 44,722 Antigens!

EEA1 antibody - N-terminal region (ARP30074_P050)

100 ul
$289.00
In Stock

Conjugation Options

ARP30074_P050-FITC Conjugated

ARP30074_P050-HRP Conjugated

ARP30074_P050-Biotin Conjugated

Gene Symbol:
EEA1
NCBI Gene Id:
8411
Official Gene Full Name:
Early endosome antigen 1
Protein Name:
Early endosome antigen 1
Swissprot Id:
Q15075
Protein Accession #:
NP_003557
Nucleotide Accession #:
NM_003566
Alias Symbols:
MST105, ZFYVE2, MSTP105
Replacement Item:
This antibody may replace item sc-137130 from Santa Cruz Biotechnology.
Description of Target:
EEA1 is involved in neuronal synaptic vesicle function and axonal transport and growth. EEA1 may undergo calcium-dependent conformational changes that are required for binding to SNAP-25.
Protein Size (# AA):
1411
Molecular Weight:
162kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, IP, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express EEA1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express EEA1.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human EEA1
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 92%; Dog: 75%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 85%; Rat: 92%
Complete computational species homology data:
Anti-EEA1 (ARP30074_P050)
Peptide Sequence:
Synthetic peptide located within the following region: LTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSAS
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; RNF2; BMI1; CFTR; ERBB2; VCP; EEA1; RAB5A; TNK2; RABEP1; RABGEF1; PDCD6IP; PXK; HDAC6; ZFYVE16; USO1; STX6; RAB22A; STX12; TOM1; RAB5C; MAPK14; RAB5B; IGF1R; NSF;
Blocking Peptide:
For anti-EEA1 (ARP30074_P050) antibody is Catalog # AAP30074 (Previous Catalog # AAPH00250)
Datasheets/Manuals:
Printable datasheet for anti-EEA1 (ARP30074_P050) antibody
Target Reference:
Fratti,R.A., et al., (2003) J. Biol. Chem. 278 (47), 46961-46967
Publications:

Cebrian, I; Croce, C; Guerrero, NA; Blanchard, N; Mayorga, LS; Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells. 17, 1753-1765 (2016). IHC, IP, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 27861124

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