Size:100 ul
$329.00
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SKU
OAGA01038
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EDN3 Antibody (OAGA01038)

Catalog#: OAGA01038
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human
Product Format Liquid
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application WB
Additional Information Background: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq]
:: Positive Controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
:: Cellular Localization: Secreted
Reconstitution and Storage Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 217 of ET-3 (Uniprot ID#P14138)
Purification Purified by antigen-affinity chromatography.
Concentration 0.52 mg/ml
Datasheets/Manuals Printable datasheet for anti-EDN3 antibody - OAGA01038
Application Info Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol EDN3
Official Gene Full Name Endothelin-3
Alias Symbols ET3 antibody, HSCR4 antibody, MGC15067 antibody, MGC61498 antibody, WS4B antibody, EDN3 antibody, endothelin-3 antibody, preproendothelin-3 antibody, endothelin 3 antibody
NCBI Gene Id 1908
Protein Name Endothelin-3
Swissprot Id P14138
Protein Accession # NP_000105.1
Molecular Weight 25 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express EDN3.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express EDN3.
  1. What is the species homology for "EDN3 Antibody (OAGA01038)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "EDN3 Antibody (OAGA01038)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "EDN3 Antibody (OAGA01038)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "EDN3 Antibody (OAGA01038)"?

    This target may also be called "ET3 antibody, HSCR4 antibody, MGC15067 antibody, MGC61498 antibody, WS4B antibody, EDN3 antibody, endothelin-3 antibody, preproendothelin-3 antibody, endothelin 3 antibody" in publications.

  5. What is the shipping cost for "EDN3 Antibody (OAGA01038)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "EDN3 Antibody (OAGA01038)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "EDN3 Antibody (OAGA01038)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "25 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "EDN3 Antibody (OAGA01038)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "EDN3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "EDN3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "EDN3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "EDN3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "EDN3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "EDN3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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