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EDC3 Antibody (OAGA01132)

100 ul
$409.00
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Gene Symbol:
EDC3
Official Gene Full Name:
Enhancer of mRNA-decapping protein 3
NCBI Gene Id:
80153
Protein Name:
Enhancer of mRNA-decapping protein 3
Swissprot Id:
Q96F86
Protein Accession #:
NP_001135915.1
Alias Symbols:
FLJ21128 antibody, FLJ31777 antibody, LSM16 antibody, YJDC antibody, YJEFN2 antibody, EDC3 antibody, yjeF N-terminal domain-containing protein 2 antibody, hYjeF_N2 antibody, yjeF domain-containing protein 1 antibody, yjeF_N2 antibody, yjeF domain containi
Replacement Item:
This antibody may replace item sc-119916 from Santa Cruz Biotechnology.
Molecular Weight:
56 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Purified by antigen-affinity chromatography.
Application:
IHC-FFPE, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express EDC3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express EDC3.
Immunogen:
Recombinant fragment corresponding to a region within amino acids 127 and 376 of Edc3 (Uniprot ID#Q96F86)
Predicted Species Reactivity:
Human, Mouse
Product Format:
Liquid
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-EDC3 antibody - OAGA01132
Isotype:
IgG
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000[suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Additional Information:
Background: EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM]
:::
Positive Controls: A431, NIH-3T3, C2C12
:::
Cellular Localization: Cytoplasm, P-body
Storage Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

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