EBV EBNA1 Protein (OPPA01828)

Catalog No: OPPA01828 (Formerly GWB-F26F91)

Size:100UG

Product Info

• Predicted Species Reactivity: Epstein-Barr Virus
• Product Format: PBS & 300mM Imidazole.
• Application: ELISA, WB
  Product Introduction: The Epstein-Barr virus (EBV), also called Human herpes virus 4 (HHV-4), is a virus of the herpes family (which includes Herpes simplex virus and Cytomegalovirus. On infecting the B-lymphocyte, the linear virus genome circularizes and the virus subsequently persists within the cell as an episome. The virus can execute several distinct programs of gene expression which can be broadly categorized as being lytic cycle or latent cycle. The lytic cycle or productive infection results in staged expression of a host of viral proteins with the ultimate objective of producing infectious virions. Formally, this phase of infection does not inevitably lead to lysis of the host cell as EBV virions are produced by budding from the infected cell. The latent cycle (lysogenic) programs are those that do not result in production of virions. A very limited, distinct set of viral proteins are produced during latent cycle infection. These include Epstein-Barr nuclear antigen (EBNA)-1, EBNA-2, EBNA-3A, EBNA-3B, EBNA-3C, EBNA-leader protein (EBNA-LP) and latent membrane proteins (LMP)-1, LMP-2A and LMP-2B and the Epstein-Barr encoded RNAs (EBERs).
  Product Description: The E.Coli derived recombinant protein contains the HHV-4 EBNA1 regions 408-641 amino acids having a molecular mass of 24.8kDa. The EBNA1 protein is fused to His Tag at N-terminus.
• Reconstitution and Storage: Protein is shipped at ambient temperature. Upon arrival, Store at -20C.
  Stability: Five years frozen. One month in solution at room temperature.
• Purity: Protein is >95% pure as determined by 10% PAGE (coomassie staining).
  Purification: Purified by proprietary chromatographic technique.
• Specificity: Immunoreactive with sera of EBV-infected individuals.
• Application Info: Antigen in ELISA and Western blots, excellent antigen for detection of HHV-4 (EBV) with minimal specificity problems.

Target Info

• Gene Symbol: EBV EBNA1 His
• Alias Symbols: EBV EBNA1, His, Epstein-Barr Virus (HHV-4) EBNA1 Recombinant, His Tag
• Description of Target: Recombinant Epstein-Barr Virus (HHV-4) EBNA1, His Tag
• Protein Size (# AA): Recombinant