EBV EBNA1 Protein (OPPA00778)

Catalog No: OPPA00778 (Formerly GWB-BSP740)

Size:100UG

The Epstein-Barr virus (EBV), also called Human herpes virus 4 (HHV-4), is a virus of the herpes family (which includes Herpes simplex virus and Cytomegalo virus. On infecting the B-lymphocyte, the linear virus genome circularizes and the virus subsequently persists within the cell as an episome. The virus can execute several distinct programs of gene expression which can be broadly categorized as being lytic cycle or latent cycle. The lytic cycleor productive infection results in staged expression of a host of viral proteins with the ultimate objective of producing infectious virions. Formally, this phase of infection does not inevitably lead to lysis of the host cell's EBV virions are produced by budding from the infected cell. The latent cycle(lysogenic) programs are those that do not result in production of virions. A very limited, distinct set of viral proteins are produced during latent cycle infection. These include Epstein-Barr nuclear antigen(EBNA)-1, EBNA-2, EBNA-3A, EBNA-3B, EBNA-3C, EBNA-leader protein (EBNA-LP) and latent membrane proteins(LMP)-1, LMP-2A and LMP-2B and the Epstein-Barr encoded RNAs(EBERs). The E.Coli derived recombinant mosaic protein contains the HHV-4 EBNA regions, 1-90, 408-498 amino acids.

Product Info

• Predicted Species Reactivity: Epstein-Barr Virus
• Product Format: Liquid 10mM PBS (pH 7.6) and 10mM NaCl
• Application: ELISA, WB
• Reconstitution and Storage: EBV EBNA1 Mosaic although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze/thaw cycles.
• Purification: Purified by proprietary chromatographic techniques.
• Concentration: 1 mg/ml
• Purity: > 95% (SDS-PAGE)
• Specificity: Immunoreactive with sera of EBV-infected individuals.
• Application Info: EBV-EBNA1 antigen is suitable for ELISA and Western blots, excellent antigen for detection of HHV-4 (EBV) with minimal specificity problems.
• Tag: C-terminal His Tag

Target Info

• Gene Symbol: EBV EBNA1
• Alias Symbols: EBV EBNA1, Epstein-Barr Virus (HHV-4) EBNA1 Recombinant
• Description of Target: Recombinant Epstein-Barr Virus (HHV-4) Mosaic EBNA1
• Protein Size (# AA): Recombinant
• Molecular Weight: 44 kDa