Ebselen (OOMC00040)

Catalog No: OOMC00040

Product Info

• Product Format: Powder
• Additional Information: CAS: 60940-34-3
  Molecular Formula: C13H9NOSe
  Chemical Name: 2-Phenyl-1,2-benzisoselenazol-3(2H)-one
  Primary Activity: Glutathione peroxidase mimic
  COVID-19 Rationale: Inhibits SARS-CoV-2 chymotrypsin-like protease (3CLpro)
• Reconstitution and Storage: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 10 mg/ml with warming). Store at room temperature.
• Purity: > 98%
• Reference: 1) Schewe et al. (1995), Molecular actions of ebselen – an anti-inflammatory antioxidant; Gen. Pharmacol., 26 1153 / 2) Parnham et al. (2000), Ebselen: prospective therapy for cerebral ischaemia; Expert. Opin. Investig. Drugs, 9 607 / 3) Masumoto et al. (1996), Kinetic study of the reaction of ebselen with peroxynitite; FEBS Lett., 398 179 / 4) Nakamura et al. (2002), Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis; J. Biol. Chem., 277 2687

Target Info

• Alias Symbols: PZ-51
• Molecular Weight: 274.18 g/mol