Size:100 ul
$329.00
In Stock
SKU
OAGA00989
Request Bulk
Order Quote
Aviva's
Satisfaction
Guarantee
Contact Us:
  • Toll Free: (888)880-0001
  • Phone: (858)552-6979
  • Email: info@avivasysbio.com
Shipping Info:
  • $40: Antibody & Protein in US
  • $50: 1-2 Kits in US
  • Contact us for international orders.

E2F1 Antibody (OAGA00989)

Catalog#: OAGA00989
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human, Mouse
Product Format Liquid
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application ICC, IF, WB
Additional Information Background: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq]
:: Positive Controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, NIH-3T3
:: Cellular Localization: Nucleus
Reconstitution and Storage Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item This antibody may replace item sc-116659 from Santa Cruz Biotechnology.
Immunogen Recombinant fragment corresponding to a region within amino acids 133 and 362 of E2F1 (Uniprot ID#Q01094)
Purification Purified by antigen-affinity chromatography.
Concentration 1 mg/ml
Datasheets/Manuals Printable datasheet for anti-E2F1 antibody - OAGA00989
Application Info Suggested starting dilutions are as follows: WB: 1:500-1:3000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol E2F1
Official Gene Full Name Transcription factor E2F1
Alias Symbols E2F-1 antibody, RBAP1 antibody, RBBP3 antibody, RBP3 antibody, E2F1 antibody, retinoblastoma-binding protein 3 antibody, RBAP-1 antibody, PRB-binding protein E2F-1 antibody, RBBP-3 antibody, transcription factor E2F1 antibody, PBR3 antibody, retinoblastom
NCBI Gene Id 1869
Protein Name Transcription factor E2F1
Swissprot Id Q01094
Protein Accession # NP_005216.1
Molecular Weight 47 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express E2F1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express E2F1.
  1. What is the species homology for "E2F1 Antibody (OAGA00989)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "E2F1 Antibody (OAGA00989)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "E2F1 Antibody (OAGA00989)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "E2F1 Antibody (OAGA00989)"?

    This target may also be called "E2F-1 antibody, RBAP1 antibody, RBBP3 antibody, RBP3 antibody, E2F1 antibody, retinoblastoma-binding protein 3 antibody, RBAP-1 antibody, PRB-binding protein E2F-1 antibody, RBBP-3 antibody, transcription factor E2F1 antibody, PBR3 antibody, retinoblastom" in publications.

  5. What is the shipping cost for "E2F1 Antibody (OAGA00989)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "E2F1 Antibody (OAGA00989)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "E2F1 Antibody (OAGA00989)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "47 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "E2F1 Antibody (OAGA00989)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "E2F1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "E2F1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "E2F1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "E2F1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "E2F1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "E2F1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:E2F1 Antibody (OAGA00989)
Your Rating
We found other products you might like!