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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for DVL2 Antibody (OACA07280) (OACA07280) |
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Predicted Species Reactivity | Human |
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Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot |
Reconstitution and Storage | -20°C or -80°C |
Immunogen | Recombinant Human Segment polarity protein dishevelled homolog DVL-2 protein (1-240AA) |
Purification | Affinity Purified |
Preservative | 0.02% sodium azide |
Formulation | PBS with, 50% glycerol, pH7.3. |
Reference | [1]"Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma."Varela I., Tarpey P., Raine K., Huang D., Ong C.K., Stephens P., Davies H., Jones D., Lin M.L., Teague J., Bignell G., Butler A., Cho J., Dalgliesh G.L., Galappaththige D., Greenman C., Hardy C., Jia M. Futreal P.A. Nature 469:539-542(2011). [2]"Crystal structure of the PDZ domains of human dishevelled 2 (homologous to Drosophila dsh)."Structural genomics consortium (SGC)Submitted (FEB-2009). [3]"Inhibition of Wnt signaling by Dishevelled PDZ peptides." Zhang Y., Appleton B.A., Wiesmann C., Lau T., Costa M., Hannoush R.N., Sidhu S.S. Nat. Chem. Biol. 5:217-219(2009). |
Gene Symbol | DVL2 |
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Gene Full Name | dishevelled segment polarity protein 2 |
Alias Symbols | dishevelled 2 (homologous to Drosophila dsh);dishevelled, dsh homolog 2;DSH homolog 2;segment polarity protein dishevelled homolog DVL-2. |
NCBI Gene Id | 1856 |
Protein Name | Segment polarity protein dishevelled homolog DVL-2 |
Description of Target | Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. |
Uniprot ID | O14641 |
Protein Accession # | NP_004413 |
Nucleotide Accession # | NM_004422 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "DVL2 Antibody (OACA07280)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "DVL2 Antibody (OACA07280)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "DVL2 Antibody (OACA07280)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "DVL2 Antibody (OACA07280)"?
This target may also be called "dishevelled 2 (homologous to Drosophila dsh);dishevelled, dsh homolog 2;DSH homolog 2;segment polarity protein dishevelled homolog DVL-2." in publications.
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What is the shipping cost for "DVL2 Antibody (OACA07280)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "DVL2 Antibody (OACA07280)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "DVL2 Antibody (OACA07280)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "DVL2 Antibody (OACA07280)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "DVL2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "DVL2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "DVL2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "DVL2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "DVL2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "DVL2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.